Pomegranate juice has very important health benefits when it comes to reducing cholesterol, LDL oxidation, and lipid peroxides. Two out of ten patients who were given PJ after 3 and 12 months have experienced clinical deterioration. They were operated in order to examine the lesions and determine the difference in composition to those who did not consume this fruit. Thus, 4 distinct positive differences have been noticed:
- “The cholesterol content in carotid lesions from the two patients that consumed PJ was lower by 58% and 20%, respectively, in comparison to lesions obtained from CAS patients that did not consume PJ (Fig. 3A).”
- “LDL oxidation by lesions derived from the patients after PJ consumption for 3 or 12 months, was significantly (Po0.01) decreased by 43% or 32%, respectively, in comparison to LDL oxidation rates obtained by lesions from CAS patients that did not consume PJ (Fig. 3D).”
- “A substantial increase in the lesion reduced glutathione (GSH) content, (GSH is a major cellular antioxidant) by 2.5-fold, was observed after PJ consumption for 3 or 12 months, (Fig. 3C).”
- “The lipid peroxides content in lesions obtained from the patients after PJ consumption for 3 or 12 months was significantly reduced by 61% or 44%, respectively, as compared to lesions from patients that did not consume PJ (Fig. 3B).”
This means that even though pomegranate can reduce the lesion size in the carotid arteries, “the lesion itself may be considered less atherogenic after PJ consumption, as its cholesterol and oxidized lipid content decreased, and since its ability to oxidize LDL was significantly reduced.”
This finding confirms that a fair amount of lipoproteins (cholesterol) in the blood cannot accurately indicate whether those lipoproteins are dangerous (atherogenic); but, if they are oxidized (e.g. ox-LDL) they can be threatening (or representative of a more systemic imbalance in the body) while non-oxidized low density lipoprotein may be regarded as entirely benign, if not crucial for heart and overall body health.
Scientists have also noticed that those who consumed pomegranate had raised triglycerides levels and very low density lipoprotein, again, showing that the anti-atherosclerotic properties may have stronger connection to the enhanced quality of the physiological milieu within which all lipoproteins operate than their number.
While all the participants took their prescribed medications for blood pressure and cholesterol-lowering, the pomegranate didn’t interfere with them.